As hiv prevention and treatment efforts expand around the globe, local capacity-building to update and maintain nurses’ hiv competence is essential. The purpose of this project was to develop and sustain a national network of nurse-trainers who could provide ongoing hiv continuing education and training experiences to vietnamese nurses. Over the course of 6 years, 87 nurses received training to become hiv trainers; their hiv knowledge increased significantly (p = .001), As did teaching self-confidence (p = .001 To .007). The 87 nurses subsequently reported training more than 67,000 health care workers. Recipients of train-the-trainer-led workshops demonstrated increased hiv knowledge (p = .001) And increased willingness to provide nursing care for hiv-infected patients (p = .001). The program demonstrated that including a substantial amount of instruction in pedagogical strategies and experiential learning could enhance knowledge transfer, expand education outreach, and contribute to sustainable hiv competence among nurses. 2014 Association of nurses in aids care.